Description

4H-Imidazo[4,5,1-Ij]Quinoline,5,6-Dihydro-8-Methoxy-(8Ci) is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 19279-85-7. This heterocyclic compound is valued for its complex fused-ring structure, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Oncology Drug Development: Serves as a core structure in the research and development of potential anti-cancer therapies.
• CNS-Active Compound Synthesis: Employed in creating molecules targeted at neurological disorders and psychiatric conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4H-Imidazo[4,5,1-Ij]Quinoline,5,6-Dihydro-8-Methoxy-(8Ci)
CAS No.	19279-85-7
Molecular Formula	C₁₁H₁₀N₂O
Molecular Weight	186.21 g/mol
Synonyms	5,6-Dihydro-8-methoxy-4H-imidazo[4,5,1-ij]quinoline; 8-Methoxy-4H,5H,6H-imidazo[4,5,1-ij]quinoline; 4H-Imidazo[4,5,1-ij]quinoline, 5,6-dihydro-8-methoxy-; 19279-85-7; Imidazo[4,5,1-ij]quinoline, 5,6-dihydro-8-methoxy-; 8-Methoxy-4H-imidazo[4,5,1-ij]quinoline
EINECS	Contact for details

Quality Control

Every batch of 4H-Imidazo[4,5,1-Ij]Quinoline,5,6-Dihydro-8-Methoxy-(8Ci) is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting cGMP-compliant development work. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), related substances, and other critical parameters are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere if found to be easily oxidized. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.