Description

1,2-Naphthalenediol, 1,2-Dihydro-, (1R,2R)-(-)- is a chiral, optically active derivative of naphthalene, serving as a crucial building block in asymmetric synthesis and pharmaceutical research. Its value lies in its role as a versatile intermediate for creating complex molecules with defined stereochemistry, which is essential for developing active pharmaceutical ingredients (APIs) and advanced materials. This high-purity compound is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on enantioselective catalysis and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel APIs, particularly where specific stereochemistry is required for biological activity.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for metal-catalyzed reactions, enabling the production of enantiomerically pure compounds.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for agrochemicals, dyes, and advanced material precursors.
• Biochemical Research: Utilized as a standard or reagent in enzymatic studies and metabolic pathway investigations due to its specific stereoconfiguration.
• Material Science Research: Acts as a monomer or modifying agent in the development of chiral polymers and functional organic materials.

Basic Information

Product Name	1,2-Naphthalenediol, 1,2-Dihydro-, (1R,2R)-(-)-
CAS No.	19216-89-8
Molecular Formula	C₁₀H₁₀O₂
Molecular Weight	162.19 g/mol
Synonyms	(-)-(1R,2R)-1,2-Dihydro-1,2-naphthalenediol; (1R,2R)-(-)-1,2-Dihydronaphthalene-1,2-diol; (1R,2R)-1,2-Dihydroxynaphthalene; L-1,2-Dihydro-1,2-naphthalenediol; (1R,2R)-1,2-Naphthalenediol; (1R,2R)-1,2-Dihydroxynaphthalene; Optically active 1,2-dihydronaphthalene-1,2-diol
EINECS	Contact for details

Quality Control

Our 1,2-Naphthalenediol, 1,2-Dihydro-, (1R,2R)-(-)- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to meet the exacting standards required for research and synthesis. Certificates of Analysis (COA) detailing specific results for identity, assay, enantiomeric excess, and impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.