Description

6-Bromo-3,4-Dihydroquinoline-2(1H)-Thione is a high-value brominated heterocyclic building block with a reactive thione group, essential for advanced synthetic chemistry. This compound matters because it serves as a critical precursor for synthesizing complex pharmacophores and functional materials, enabling the development of novel compounds with tailored properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of quinoline-based drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging the bioactivity of the quinoline-thione scaffold.
• Ligand Synthesis: Serves as a precursor for creating complex chelating ligands in coordination chemistry and catalysis.
• Material Science: Employed in the research and development of organic electronic materials and photoactive compounds.
• Chemical Biology: Utilized as a probe or building block in the study of enzyme inhibition and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Bromo-3,4-Dihydroquinoline-2(1H)-Thione
CAS No.	19205-72-2
Molecular Formula	C9H8BrNS
Molecular Weight	242.14 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydro-2-quinolinethione; 6-Bromo-3,4-dihydro-2(1H)-quinolinethione; 6-Bromo-1,2,3,4-tetrahydroquinoline-2-thione; 2(1H)-Quinolinethione, 6-bromo-3,4-dihydro-; 6-Bromotetrahydro-2-quinolinethione; 19205-72-2; 6-Bromo-3,4-dihydro-2-mercaptoquinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-3,4-Dihydroquinoline-2(1H)-Thione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation, adhering to cGMP standards where applicable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.