Description

[(3R,4S)-3-[(4R)-2,2-Dimethyl-1,3-Dioxolan-4-Yl]-7,7-Dimethyl-2,6,8-Trioxabicyclo[3.3.0]Oct-4-Yl]Oxy-Phenoxy-Methanethione is a sophisticated chiral building block and protected intermediate of significant value in advanced organic synthesis. Its complex, rigid bicyclic structure with multiple protecting groups makes it a critical precursor for the stereoselective construction of complex molecules, particularly in pharmaceutical research. This compound is essential for chemists and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in antiviral, anticancer, and neurological therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides that require specific stereoisomers for optimal activity.
• Asymmetric Catalysis Research: Serves as a valuable ligand precursor or a model substrate for developing and testing new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, flavors, and fragrances that demand high stereochemical purity.
• Academic & R&D Laboratories: A crucial compound for university and institutional research focused on novel synthetic routes and natural product synthesis.

Basic Information

Product Name	[(3R,4S)-3-[(4R)-2,2-Dimethyl-1,3-Dioxolan-4-Yl]-7,7-Dimethyl-2,6,8-Trioxabicyclo[3.3.0]Oct-4-Yl]Oxy-Phenoxy-Methanethione
CAS No.	19189-62-9
Molecular Formula	C19H24O7S
Molecular Weight	396.45 g/mol
Synonyms	(3R,4S)-3-[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl]-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]oct-4-yl O-phenyl carbonothioate; Phenyl (3R,4S)-3-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]octan-4-yl carbonothioate; Protected Thiocarbonate Intermediate; Chiral Bicyclic Thiocarbonate; CAS 19189-62-9; Bicyclo[3.3.0]octane thiocarbonate derivative
EINECS	Contact for details

Quality Control

We supply [(3R,4S)-3-[(4R)-2,2-Dimethyl-1,3-Dioxolan-4-Yl]-7,7-Dimethyl-2,6,8-Trioxabicyclo[3.3.0]Oct-4-Yl]Oxy-Phenoxy-Methanethione with a commitment to the highest standards of purity and consistency. Our products undergo rigorous quality testing including chiral HPLC, NMR, and LC-MS to ensure compliance with stringent research and development requirements. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every batch to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.