Description

8-Quinazolinecarboxylic Acid, 3,4-Dihydro-4-Oxo- is a high-purity, versatile heterocyclic carboxylic acid derivative that serves as a critical synthetic intermediate. Its core value lies in its fused quinazoline-4-one scaffold, which is a privileged structure in medicinal chemistry for designing bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting kinases, enzymes, and various receptors.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex polycyclic compounds and functionalized quinazoline derivatives.
• Biochemical Tool Compound: Utilized in biochemical assays and as a scaffold for probing biological pathways and protein interactions.
• Material Science Research: Investigated as a potential monomer or functional component for advanced organic materials and polymers.

Basic Information

Product Name	8-Quinazolinecarboxylic Acid, 3,4-Dihydro-4-Oxo-
CAS No.	19181-77-2
Molecular Formula	C9H6N2O3
Molecular Weight	190.16 g/mol
Synonyms	4-Oxo-3,4-dihydroquinazoline-8-carboxylic acid; 8-Carboxy-3,4-dihydro-4-oxoquinazoline; 3,4-Dihydro-4-oxoquinazoline-8-carboxylic acid; Quinazoline-8-carboxylic acid, 3,4-dihydro-4-oxo-; 4-Hydroxyquinazoline-8-carboxylic acid; 8-Quinazolinecarboxylic acid, 4-hydroxy-
EINECS	Contact for details

Quality Control

Our 8-Quinazolinecarboxylic Acid, 3,4-Dihydro-4-Oxo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.