Description

(S)-(-)-1-Amino-1-Phenylpropanehcl CAS NO 19146-52-2 is a high-purity chiral amine salt, specifically the hydrochloride salt of (S)-(-)-1-amino-1-phenylpropane. This compound is a critical chiral building block and resolving agent, valued for its ability to impart stereoselectivity in complex chemical syntheses. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for the development of active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand: Used as a precursor or component in the preparation of chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Chiral Resolving Agent: Employed for the optical resolution of racemic mixtures of acids or other compounds via diastereomeric salt formation.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically specific herbicides, fungicides, and plant growth regulators.
• Fine Chemical & Material Science: Utilized in the research and production of advanced materials, liquid crystals, and specialty polymers where chirality influences material properties.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(S)-(-)-1-Amino-1-Phenylpropanehcl
CAS No.	19146-52-2
Molecular Formula	C9H14ClN
Molecular Weight	171.67 g/mol
Synonyms	(S)-(-)-1-Amino-1-phenylpropane hydrochloride; (S)-1-Phenylpropylamine hydrochloride; (S)-(-)-1-Phenylpropylamine HCl; (S)-α-Methylbenzylamine hydrochloride; (S)-(-)-α-Methylbenzylamine hydrochloride; (S)-1-Amino-1-phenylpropane HCl; (S)-Amphetamine hydrochloride; L-(-)-α-Methylbenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-(-)-1-Amino-1-Phenylpropanehcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and specific rotation is provided with every shipment. We can support development projects requiring compliance with ICH guidelines or other regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Specific Rotation [α]	-30° to -35° (c=1 in H2O)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.