Description

n-Stearoylhistidine is a synthetic lipoamino acid derivative, formed by the conjugation of stearic acid with the amino acid L-histidine. This compound is valued for its unique amphiphilic properties, combining the hydrophobic character of a long-chain fatty acid with the hydrophilic, biologically active imidazole moiety of histidine. It is primarily sought by research and development teams in the cosmetic, pharmaceutical, and advanced material science industries for its potential as a skin-conditioning agent, a biocompatible surfactant, or a building block for novel biomaterials.

Application

• Cosmetic & Personal Care Actives: Serves as a key ingredient in anti-aging and moisturizing formulations, leveraging its skin-barrier reinforcing and conditioning properties.
• Pharmaceutical Intermediates: Used in the research and synthesis of prodrugs or novel drug delivery systems designed for enhanced bioavailability.
• Biomaterial Fabrication: Acts as a functional monomer or surfactant in the development of biocompatible polymers, hydrogels, and nano-carriers.
• Biochemical Research: Employed as a model compound in studies of lipid-protein interactions, membrane biophysics, and enzyme inhibition.
• Specialty Surfactants: Functions as a mild, amino acid-based surfactant or emulsifier in high-value niche formulations.

Basic Information

Product Name	n-Stearoylhistidine
CAS No.	19132-64-0
Molecular Formula	C24H43N3O3
Molecular Weight	421.62 g/mol
Synonyms	Nα-Stearoyl-L-histidine; L-Histidine, N-stearoyl-; Stearic acid histidine amide; Histidine stearamide; N-(1-Oxooctadecyl)histidine; Lipamino acid SA-H; Nα-Octadecanoyl-L-histidine
EINECS	Contact for details

Quality Control

Our n-Stearoylhistidine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and industrial use. A Certificate of Analysis (COA) detailing the results for each specific lot is provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.