Description

3-(2,4-Difluoro-Phenyl)-2-Mercapto-3H-Quinazolin-4-One is a specialized heterocyclic organic compound featuring a quinazolinone core substituted with a difluorophenyl group and a mercapto moiety. This unique molecular structure makes it a valuable pharmaceutical intermediate and key building block in advanced organic synthesis. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the biological activity of the quinazolinone and difluorophenyl motifs.
• Organic Synthesis Building Block: Employed in complex organic reactions, including cross-coupling and cyclization, to construct more elaborate heterocyclic systems for material science and chemical research.
• Biochemical Research: Acts as a ligand or a probe in biochemical assays to study protein interactions and enzyme mechanisms due to its specific functional groups.
• Material Science Precursor: Investigated for the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), or specialty polymers.

Basic Information

Product Name	3-(2,4-Difluoro-Phenyl)-2-Mercapto-3H-Quinazolin-4-One
CAS No.	19062-31-8
Molecular Formula	C₁₄H₈F₂N₂OS
Molecular Weight	290.29 g/mol
Synonyms	2-Mercapto-3-(2,4-difluorophenyl)-4(3H)-quinazolinone; 3-(2,4-Difluorophenyl)-2-mercapto-4(3H)-quinazolinone; 2-Thiol-3-(2,4-difluorophenyl)-4(3H)-quinazolinone; 19062-31-8; 3-(2,4-Difluorophenyl)-2-sulfanyl-3H-quinazolin-4-one; 4(3H)-Quinazolinone, 3-(2,4-difluorophenyl)-2-mercapto-; 2-Mercapto-3-(2,4-difluorophenyl)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our production of 3-(2,4-Difluoro-Phenyl)-2-Mercapto-3H-Quinazolin-4-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.