Description

Spiro[4.5]Decane-8-Carboxylic Acid CAS NO 19027-23-7 is a specialized spirocyclic carboxylic acid building block prized for its unique three-dimensional structure and functional handle. This compound is critical for introducing conformational rigidity and specific steric profiles into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, catalyst design, and the synthesis of complex organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where its spirocyclic core can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in the creation of sophisticated chiral ligands and organocatalysts for asymmetric synthesis, improving reaction selectivity and yield.
• Material Science Research: Acts as a monomer or additive in the development of specialty polymers and advanced organic materials with tailored physical properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Product Name	Spiro[4.5]Decane-8-Carboxylic Acid
CAS No.	19027-23-7
Molecular Formula	C11H18O2
Molecular Weight	182.26 g/mol
Synonyms	8-Carboxyspiro[4.5]decane; Spiro[4.5]decane-8-carboxylic acid; 1,1'-Bicyclopentyl-1-carboxylic acid; 8-Spiro[4.5]decane carboxylic acid; 1-Carboxyspiro[4.5]decane; 1,1'-Spirobi(cyclopentane)-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our Spiro[4.5]Decane-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.