Description

3-o-Methyl-1,2:5,6-Di-o-Isopropylidene-α-D-Ribo-Hexofuranose is a high-purity, protected carbohydrate derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, stereochemically defined scaffold for constructing complex molecules, particularly nucleoside analogs and other bioactive compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality starting materials for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of nucleoside analogs and antiviral/antitumor agents.
• Organic Synthesis Building Block: Used for constructing complex sugar-modified molecules and natural product analogs.
• Glycochemistry Research: Valuable intermediate for studying carbohydrate chemistry and developing new glycosylation methodologies.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Bioconjugate Development: Serves as a linker or spacer in the creation of targeted drug delivery systems and diagnostic probes.
• Academic & R&D: Fundamental reagent in university and industrial research laboratories for exploring new chemical entities.

Basic Information

Product Name	3-o-Methyl-1,2:5,6-Di-o-Isopropylidene-α-D-Ribo-Hexofuranose
CAS No.	18968-49-5
Molecular Formula	C13H22O6
Molecular Weight	274.31 g/mol
Synonyms	3-O-Methyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose; 3-O-Methyl-1,2:5,6-di-O-isopropylidene-α-D-ribo-hexofuranose; 3-O-Methyl-di-O-isopropylideneallose; 1,2:5,6-Di-O-isopropylidene-3-O-methyl-α-D-allofuranose; 3-Methyl Ether of 1,2:5,6-Di-O-isopropylidene-α-D-allofuranose; Protected D-Allose Derivative
EINECS	Contact for details

Quality Control

Our 3-o-Methyl-1,2:5,6-Di-o-Isopropylidene-α-D-Ribo-Hexofuranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-30° to -35° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.