Description

1-Bromo-3-Chlorobenzene is a versatile halogenated aromatic compound, also known as meta-bromochlorobenzene, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen atoms on the benzene ring, making it an essential intermediate for constructing complex molecules in pharmaceuticals and agrochemicals. This high-purity intermediate is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for coupling reactions and further functionalization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a meta-disubstituted benzene scaffold.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides where the bromo and chloro groups act as handles for further chemical modification.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions like Suzuki and Buchwald-Hartwig amination.
• Material Science: Employed in the production of liquid crystals, organic semiconductors, and advanced polymers requiring specific halogenated aromatic units.
• Dyestuff and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	1-Bromo-3-Chlorobenzene
CAS No.	108-37-2
Molecular Formula	C6H4BrCl
Molecular Weight	191.45 g/mol
Synonyms	m-Bromochlorobenzene; 3-Bromochlorobenzene; 3-Chlorobromobenzene; 1-Chloro-3-bromobenzene; meta-Chlorobromobenzene; Benzene, 1-bromo-3-chloro-; (3-Chlorophenyl)bromide
EINECS	203-576-6

Quality Control

Our 1-Bromo-3-Chlorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.5%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.63 - 1.65 g/mL
Boiling Point	196 - 198 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.