Description

Methyl 2-Hexynoate is a specialized alkyne ester with the CAS number 18937-79-6, serving as a versatile building block in advanced organic synthesis. Its terminal alkyne and ester functionalities make it a valuable precursor for constructing complex molecular architectures through coupling and cycloaddition reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty fragrance industries seeking to develop novel active ingredients and high-value intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of bioactive molecules and potential drug candidates via click chemistry and Sonogashira coupling.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactivity to create diverse heterocyclic structures.
• Fragrance & Flavor Chemistry: Acts as a precursor for synthesizing unique aroma chemicals with fruity or green notes, given its ester backbone and potential for derivatization.
• Material Science: Employed in the synthesis of monomers and polymers with tailored properties for advanced coatings and functional materials.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new catalytic methodologies and constructing complex natural product analogs.
• Chemical Biology: Useful as a probe or linker in bioconjugation strategies due to its alkyne handle for bioorthogonal reactions.

Basic Information

Product Name	Methyl 2-Hexynoate
CAS No.	18937-79-6
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	2-Hexynoic acid, methyl ester; Methyl hex-2-ynoate; Methyl hexynoate; Methyl 2-hexynoate; Methyl pentylpropiolate; Methyl 2-butylethynoate; Methyl (2-butylethynyl)carboxylate; 2-Hexynoic acid methyl ester
EINECS	242-707-5

Quality Control

Our Methyl 2-Hexynoate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.430 - 1.440
Density (20°C)	0.92 - 0.96 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.