Description

Methyl 2-Amino-3-Methylpentanoate is a high-purity chiral amino acid ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected, activated form of the non-proteinogenic amino acid 2-amino-3-methylpentanoic acid, enabling precise and efficient peptide coupling and molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs), peptide mimetics, and complex chiral intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel therapeutic peptides, protease inhibitors, and other bioactive molecules.
• Peptide Chemistry: Used as a protected amino acid ester in solid-phase and solution-phase peptide synthesis (SPPS) to introduce specific structural features.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in catalytic asymmetric reactions to construct complex stereocenters.
• Biochemical Research: Employed in studying enzyme mechanisms, substrate specificity, and as a standard in analytical method development.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, advanced materials, and ligands for catalysis.
• Agrochemical Research: Potential building block for developing new chiral active ingredients with specific biological activity.

Basic Information

Product Name	Methyl 2-Amino-3-Methylpentanoate
CAS No.	18869-44-8
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	Methyl 2-Amino-3-methylvalerate; L-Isoleucine methyl ester; Methyl L-isoleucinate; 2-Amino-3-methylpentanoic acid methyl ester; Methyl (2S,3S)-2-amino-3-methylpentanoate; Isoleucine methyl ester; Methyl α-amino-β-methylvalerate
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-3-Methylpentanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and cGMP-grade synthesis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.