Description

Di-o-Tolylphenylphosphine is a specialized organophosphorus compound widely used as a ligand in transition metal catalysis. Its value lies in its ability to modulate the reactivity and selectivity of metal catalysts, particularly in cross-coupling reactions essential for fine chemical and pharmaceutical synthesis. This product is critical for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable ligands for developing new synthetic pathways.

Application

• As a ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Negishi couplings, for C-C bond formation.
• Key component in homogeneous catalyst systems for the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).
• Used in olefin polymerization and oligomerization catalysts for the production of specialty polymers.
• Employed in asymmetric hydrogenation and hydroformylation catalysts to achieve chiral selectivity.
• Research and development of new catalytic processes in academic and industrial laboratories.
• Precursor for the synthesis of more complex phosphine ligands and organometallic complexes.

Basic Information

Product Name	Di-o-Tolylphenylphosphine
CAS No.	18803-09-3
Molecular Formula	C20H19P
Molecular Weight	290.34 g/mol
Synonyms	Di(2-methylphenyl)phenylphosphine; Bis(o-tolyl)phenylphosphine; P,P-Di-o-tolylphenylphosphine; Phenylbis(2-methylphenyl)phosphine; 2,2'-Dimethyltriphenylphosphine; (2-Methylphenyl)phenylphosphine (dimer-related); Di-ortho-tolylphenylphosphine
EINECS	Contact for details

Quality Control

Our Di-o-Tolylphenylphosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for catalytic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.