Description

1-(2-Bromoethoxy)-3-(Trifluoromethyl)Benzene is a versatile and high-value aromatic building block containing both a bromoethoxy linker and a trifluoromethyl group. This combination of functional groups makes it a critical intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts desirable properties like metabolic stability and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays.
• Polymer Modification: Employed to introduce functional side chains into polymers, altering their physical and chemical properties.
• Cross-coupling Reactions: The bromoethoxy moiety acts as a handle for palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination.
• Ligand & Catalyst Development: Useful for creating novel chelating agents and catalysts for asymmetric synthesis.

Basic Information

Product Name	1-(2-Bromoethoxy)-3-(Trifluoromethyl)Benzene
CAS No.	18800-39-0
Molecular Formula	C9H8BrF3O
Molecular Weight	269.06 g/mol
Synonyms	3-(Trifluoromethyl)phenethyl bromide; 2-Bromoethyl 3-(Trifluoromethyl)phenyl ether; 1-Bromo-2-[3-(trifluoromethyl)phenoxy]ethane; m-Trifluoromethylphenoxyethyl bromide; 3-Trifluoromethylphenoxyethyl bromide; 2-(3-Trifluoromethylphenoxy)ethyl bromide; α-Bromo-3-trifluoromethylphenetole
EINECS	Contact for details

Quality Control

Our 1-(2-Bromoethoxy)-3-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.