Description

2,2,5,5-Tetramethyl-4-Phenyl-3-Imidazoline-3-Oxide-1-Oxyl is a stable nitroxide radical, specifically a member of the imidazoline nitroxide family. This compound is a crucial spin label and spin trap in electron paramagnetic resonance (EPR) spectroscopy, enabling the study of molecular dynamics, structure, and free radical processes. It is essential for researchers and manufacturers in advanced materials science, polymer chemistry, and life sciences who require precise tools for probing molecular environments and oxidative mechanisms.

Application

• Spin Labeling in EPR Spectroscopy: Used as a stable radical probe to study the dynamics, conformation, and local environment of polymers, proteins, and membranes.
• Spin Trapping Agent: Employed to detect and identify short-lived free radicals in chemical and biological systems for mechanistic studies.
• Polymer Chemistry: Acts as a mediator in controlled/living radical polymerization (e.g., Nitroxide-Mediated Polymerization - NMP) to synthesize polymers with well-defined architectures.
• Antioxidant Research: Serves as a model compound to evaluate antioxidant activity and understand oxidative stress pathways.
• Materials Science: Incorporated into organic magnetic materials and molecular devices due to its persistent radical character.
• Biophysical Probes: Utilized to label biomolecules for investigating structure-function relationships via site-directed spin labeling (SDSL).
• Catalysis: Applied in oxidation catalysis and as a redox-active ligand or catalyst component.
• Reference Standard: Used as a calibration standard in analytical chemistry and EPR instrumentation.

Basic Information

Product Name	2,2,5,5-Tetramethyl-4-Phenyl-3-Imidazoline-3-Oxide-1-Oxyl
CAS No.	18796-03-7
Molecular Formula	C₁₃H₁₇N₂O₂
Molecular Weight	233.29 g/mol
Synonyms	4-Phenyl-2,2,5,5-tetramethyl-3-imidazoline-1-oxyl-3-oxide; 4-Phenyl-2,2,5,5-tetramethylimidazoline-1-oxyl-3-oxide; PTIO; 2,2,5,5-Tetramethyl-4-phenyl-3-imidazoline-3-oxide-1-oxyl radical; 4-Phenyl-2,2,5,5-tetramethyl-δ³-imidazoline-3-oxide-1-oxyl; PTIO radical; 18796-03-7; 4-Phenyl-2,2,5,5-tetramethyl-3-imidazolin-1-oxyl-3-oxide
EINECS	Contact for details

Quality Control

Our 2,2,5,5-Tetramethyl-4-Phenyl-3-Imidazoline-3-Oxide-1-Oxyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, EPR spectroscopy for radical content verification, and comprehensive identification tests. We provide full traceability and detailed Certificates of Analysis (COA) upon request, ensuring the material meets the high standards required for research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and maintain stability. Keep away from strong reducing agents.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
EPR Analysis	Confirms characteristic nitroxide radical signal
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.