Description

(R)-(+)-2,2'-Diamino-1,1'-Binaphthalene CAS NO 18741-85-0 is a high-purity, enantiomerically pure chiral diamine derivative of 1,1'-binaphthyl, widely recognized as a versatile and privileged chiral scaffold. This compound matters significantly for its role as a key building block and ligand in asymmetric synthesis, enabling the production of enantiomerically enriched pharmaceuticals and fine chemicals. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise chirality control in their catalytic processes and molecular designs.

Application

• Asymmetric Catalysis: Serves as a precursor for chiral ligands (e.g., BINAM-derived phosphines, N-heterocyclic carbenes) used in metal-catalyzed reactions like hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediates: A critical chiral building block in the synthesis of active pharmaceutical ingredients (APIs) where specific enantiomeric purity is required for efficacy and safety.
• Chiral Resolution Agents: Used to synthesize chiral stationary phases for HPLC or as chiral auxiliaries and resolving agents for the separation of racemic mixtures.
• Supramolecular Chemistry & Sensors: Employed in the construction of chiral molecular receptors, frameworks, and fluorescent sensors due to its rigid, V-shaped structure and amine functionality.
• Polymer Science: Acts as a monomer for creating chiral polymers and advanced materials with unique optical or electronic properties.
• Agrochemical Synthesis: Utilized in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	(R)-(+)-2,2'-Diamino-1,1'-Binaphthalene
CAS No.	18741-85-0
Molecular Formula	C₂₀H₁₆N₂
Molecular Weight	284.36 g/mol
Synonyms	(R)-(+)-1,1'-Binaphthyl-2,2'-diamine; (R)-BINAM; (R)-2,2'-Diamino-1,1'-binaphthyl; (R)-1,1'-Bi-2-naphthylamine; (R)-[1,1'-Binaphthalene]-2,2'-diamine; (R)-2,2'-Diamino[1,1'-binaphthalene]; (R)-DABN; (R)-BINOL diamine
EINECS	Contact for details

Quality Control

Our (R)-(+)-2,2'-Diamino-1,1'-Binaphthalene is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and standard purity assays. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards as required for global pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity. Keep the container tightly sealed in a dry environment to minimize contact with moisture and air.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.