Description

Diethyl (3-Chloropropyl)Malonate is a versatile bifunctional chemical intermediate featuring both an active methylene group and a reactive chloropropyl moiety. This compound is essential for the synthesis of complex molecules, enabling key carbon-carbon bond formation and nucleophilic substitution reactions. It is primarily sought after by manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for producing active ingredients and fine chemicals.

Application

• Pharmaceutical Synthesis: A key building block for the production of various active pharmaceutical ingredients (APIs), particularly those containing carboxylic acid derivatives and heterocyclic compounds.
• Agrochemical Intermediates: Used in the manufacture of herbicides, fungicides, and plant growth regulators, where its structure allows for the introduction of specific functional groups.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty organic compounds requiring malonate ester chemistry.
• Polymer Modification: Employed in the synthesis of monomers or as a cross-linking agent for specialty polymers and resins.
• Organic Synthesis Reagent: Utilized in academic and industrial R&D for annulation reactions, cyclopropanation, and the synthesis of complex natural product analogs.

Basic Information

Product Name	Diethyl (3-Chloropropyl)Malonate
CAS No.	18719-43-2
Molecular Formula	C10H17ClO4
Molecular Weight	236.69 g/mol
Synonyms	3-Chloropropylmalonic Acid Diethyl Ester; Diethyl 3-Chloropropylmalonate; Propanedioic acid, 2-(3-chloropropyl)-, 1,3-diethyl ester; Malonic acid, (3-chloropropyl)-, diethyl ester; (3-Chloropropyl)malonic acid diethyl ester; Diethyl (γ-chloropropyl)malonate; 1,3-Diethyl 2-(3-chloropropyl)propanedioate
EINECS	242-522-9

Quality Control

Our Diethyl (3-Chloropropyl)Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.435 - 1.445
Density (20°C)	1.10 - 1.15 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.