Description

4-Bromo-6-Methoxy-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of bromine, methoxy, and trifluoromethyl substituents on the quinoline scaffold, enabling precise molecular modifications for the development of novel compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-infectives, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and metabolic stability.
• Material Science: Acts as a building block for creating advanced organic electronic materials, such as ligands for OLEDs or components for organic semiconductors.
• Chemical Synthesis: The bromine atom provides a versatile handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Heck), enabling the construction of complex molecular architectures.
• Fluorine Chemistry: The stable trifluoromethyl group is valuable for introducing fluorine into target molecules, a common strategy to modulate lipophilicity, metabolic stability, and binding affinity.

Basic Information

Product Name	4-Bromo-6-Methoxy-2-(Trifluoromethyl)Quinoline
CAS No.	18706-38-2
Molecular Formula	C₁₁H₇BrF₃NO
Molecular Weight	306.08 g/mol
Synonyms	4-Bromo-6-methoxy-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-bromo-6-methoxyquinoline; 6-Methoxy-4-bromo-2-trifluoromethylquinoline; Quinoline, 4-bromo-6-methoxy-2-(trifluoromethyl)-; 4-Bromo-6-methoxy-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-6-Methoxy-2-(Trifluoromethyl)Quinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.