Description

4-Bromo-6-Chloro-2-(Trifluoromethyl)Quinoline is a high-value, multi-halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it an essential intermediate for developing novel compounds with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Building block for developing next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Used in the creation of organic semiconductors, liquid crystals, and advanced polymers due to its electron-deficient quinoline core.
• Chemical Synthesis: Versatile scaffold for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Fluorine Chemistry: The trifluoromethyl group makes it a valuable reagent for introducing fluorine atoms into target molecules to modulate bioavailability and metabolic stability.

Basic Information

Product Name	4-Bromo-6-Chloro-2-(Trifluoromethyl)Quinoline
CAS No.	18706-32-6
Molecular Formula	C₁₀H₄BrClF₃N
Molecular Weight	310.50 g/mol
Synonyms	4-Bromo-6-chloro-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-bromo-6-chloroquinoline; Quinoline, 4-bromo-6-chloro-2-(trifluoromethyl)-; 4-Bromo-6-chloro-2-trifluoromethylquinoline; 18706-32-6; 4-Br-6-Cl-2-CF3-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Chloro-2-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity data, identity confirmation (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply for critical development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.