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4-Bromo-6-Methyl-2-(Trifluoromethyl)Quinoline CAS NO 18706-27-9


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CAS No.:18706-27-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Bromo-6-Methyl-2-(Trifluoromethyl)Quinoline is a high-purity, halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine and trifluoromethyl substituents, makes it an invaluable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
  • Agrochemical Research: Used to construct advanced scaffolds for next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
  • Material Science: Serves as a monomer or functional additive in the development of specialty polymers, organic semiconductors, and liquid crystals due to its electron-deficient aromatic system.
  • Catalyst Ligand Synthesis: Employed in the preparation of sophisticated nitrogen-containing ligands for transition metal catalysis in fine chemical manufacturing.
  • Fluorescent Probe Development: The bromine atom provides a handle for further functionalization (e.g., via cross-coupling) to create dyes and sensors for analytical and diagnostic applications.

Basic Information

Product Name 4-Bromo-6-Methyl-2-(Trifluoromethyl)Quinoline
CAS No. 18706-27-9
Molecular Formula C₁₁H₇BrF₃N
Molecular Weight 290.08 g/mol
Synonyms 4-Bromo-6-methyl-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-bromo-6-methylquinoline; 6-Methyl-4-bromo-2-trifluoromethylquinoline; Quinoline, 4-bromo-6-methyl-2-(trifluoromethyl)-; 18706-27-9; 4-Bromo-6-methyl-2-trifluoromethylquinoline
EINECS Contact for details

Quality Control

Our 4-Bromo-6-Methyl-2-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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