Description

2-(Trifluoromethyl)Quinoline-4-Carbonitrile is a high-purity, fluorinated quinoline derivative with a nitrile functional group, serving as a critical advanced intermediate in organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functional additive in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the exploration of new heterocyclic chemistry.
• Fluorine Chemistry: A valuable substrate for studying fluorination reactions and the introduction of fluorine-containing motifs into complex molecules.

Basic Information

Product Name	2-(Trifluoromethyl)Quinoline-4-Carbonitrile
CAS No.	18706-26-8
Molecular Formula	C11H5F3N2
Molecular Weight	222.17 g/mol
Synonyms	4-Cyano-2-(trifluoromethyl)quinoline; Quinoline-4-carbonitrile, 2-(trifluoromethyl)-; 2-Trifluoromethylquinoline-4-carbonitrile; 2-(Trifluoromethyl)-4-cyanoquinoline; 2-(Trifluoromethyl)-4-quinolinecarbonitrile; 4-Quinolinecarbonitrile, 2-(trifluoromethyl)-; 18706-26-8
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Quinoline-4-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.