Description

1-[[(1R,8Ar)-2,3,4,5,6,7,8,8A-Octahydro-1H-Quinolizin-1-Yl]Methyl]Pipe Ridine-2,6-Dione is a complex, stereochemically defined heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its unique fused ring structure, which provides a versatile scaffold for constructing pharmacologically active molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on developing novel alkaloid-based therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of novel, high-efficacy pesticides and herbicides that leverage its complex alkaloid-like backbone.
• Academic & Contract Research: Serves as a valuable reference standard and starting material for methodological studies in organic chemistry and medicinal chemistry programs.
• Process Chemistry Development: Employed in scaling up synthetic routes for candidate drugs, where consistent quality and stereochemical purity are paramount.
• Ligand & Catalyst Design: Its structure can be modified to create novel chiral ligands for asymmetric catalysis.

Basic Information

Product Name	1-[[(1R,8Ar)-2,3,4,5,6,7,8,8A-Octahydro-1H-Quinolizin-1-Yl]Methyl]Pipe Ridine-2,6-Dione
CAS No.	18688-40-9
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	(1R,8aR)-1-[(2,6-Dioxopiperidin-1-yl)methyl]octahydro-2H-quinolizine; 1-[[(1R,8aR)-Octahydro-2H-quinolizin-1-yl]methyl]piperidine-2,6-dione; (1R,8aR)-1-[(2,6-Dioxopiperidin-1-yl)methyl]decahydroquinolizine; 1-((1R,8aR)-Octahydro-2H-quinolizin-1-yl)methyl)piperidine-2,6-dione; 1-[(1R,8aR)-Octahydro-2H-quinolizin-1-ylmethyl]piperidine-2,6-dione; 18688-40-9; (R)-1-((Octahydro-2H-quinolizin-1-yl)methyl)piperidine-2,6-dione
EINECS	Contact for details

Quality Control

Our production of 1-[[(1R,8Ar)-2,3,4,5,6,7,8,8A-Octahydro-1H-Quinolizin-1-Yl]Methyl]Pipe Ridine-2,6-Dione adheres to stringent in-process controls and final release testing to ensure exceptional chemical purity and stereochemical integrity. Each batch is fully characterized using advanced analytical techniques, including chiral HPLC and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97%), enantiomeric excess, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.