Description

[1S-(1Alpha,2Alpha,5Alpha)]-6,6-Dimethylspiro[Bicyclo[3.1.1]Heptane-2,2'-Oxirane] is a high-purity, chiral spirocyclic epoxide building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional structure and reactive oxirane ring make it a versatile precursor for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with enhanced efficacy and stereospecificity.
• Ligand and Catalyst Development: Used to prepare sophisticated chiral ligands and organocatalysts for asymmetric synthesis.
• Fragrance and Flavor Chemistry: Serves as a starting material for synthesizing unique terpene-derived aroma compounds.
• Material Science Research: Precursor for epoxy resins and polymers with specialized thermal or mechanical properties derived from its rigid core.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening reactions and cascade cyclizations.

Basic Information

Product Name	[1S-(1Alpha,2Alpha,5Alpha)]-6,6-Dimethylspiro[Bicyclo[3.1.1]Heptane-2,2'-Oxirane]
CAS No.	18680-30-3
Molecular Formula	C11H16O
Molecular Weight	164.24 g/mol
Synonyms	(1S,2S,5S)-6,6-Dimethylspiro[bicyclo[3.1.1]heptane-2,2'-oxirane]; (-)-Myrtenal oxide; (1S,5S)-6,6-Dimethyl-2-oxaspiro[bicyclo[3.1.1]heptane-2,2'-oxirane]; L-Myrtenal oxide; Spiro[2.4]heptane, 5,5-dimethyl-6-oxabicyclo[3.1.1]hept-2-yl-, (1S,2S,5S)-; (-)-6,6-Dimethylspiro[bicyclo[3.1.1]hept-2-ene-2,2'-oxirane] (related unsaturated form); Myrtenal Epoxide; Chiral Spiro Epoxide
EINECS	Contact for details

Quality Control

Our [1S-(1Alpha,2Alpha,5Alpha)]-6,6-Dimethylspiro[Bicyclo[3.1.1]Heptane-2,2'-Oxirane] is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to preserve optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.