Description

3-Hydroxyazetidine Hydrochloride is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting the central nervous system. Pharmaceutical researchers and fine chemical manufacturers need it for constructing complex molecular architectures, especially in the synthesis of β-lactam analogs and other nitrogen-containing heterocycles with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in neuroscience and antibiotic research.
• Organic Synthesis Building Block: Used in the construction of complex azetidine and pyrrolidine derivatives for medicinal chemistry.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation Chemistry: Utilized in the modification of peptides and proteins due to its reactive hydroxyl and amine functionalities.
• Material Science Research: Investigated as a monomer or cross-linking agent for novel polymeric materials.
• Agrochemical Synthesis: Employed in the research and development of new crop protection agents with novel modes of action.

Basic Information

Product Name	3-Hydroxyazetidine Hydrochloride
CAS No.	18621-18-6
Molecular Formula	C3H8ClNO
Molecular Weight	109.55 g/mol
Synonyms	3-Hydroxyazetidine HCl; Azetidin-3-ol hydrochloride; 3-Azetidinol hydrochloride; 1-Azacyclobutan-3-ol hydrochloride; 3-Hydroxy-1-azacyclobutane hydrochloride; 3-Azetidinol, hydrochloride; 3-Hydroxyazacyclobutane hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Hydroxyazetidine Hydrochloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.