Description

(2S,4S,5R,6R)-5-Acetamido-6-(1-Acetyloxy-2,3-Dihydroxypropyl)-2,4-Dihydroxyoxane-2-Carboxylic Acid is a high-purity, stereochemically defined carbohydrate derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for the development of novel therapeutics, particularly in the glycoscience and antiviral fields. It is essential for research and development laboratories in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of complex active pharmaceutical ingredients (APIs), especially nucleoside analogs and glycosidase inhibitors.
• Glycobiology Research: Used as a building block for constructing oligosaccharides, glycoconjugates, and glycomimetics to study carbohydrate-protein interactions.
• Antiviral Drug Development: Potential intermediate in the research and synthesis pathway for investigational antiviral compounds.
• Chemical Biology Probes: Serves as a starting material for labeling or modifying biomolecules to study biological processes.
• Enzyme Substrate/Analog: Acts as a substrate or inhibitor for enzymatic studies targeting glycosyltransferases or hydrolases.
• Fine Chemical Synthesis: Valuable intermediate for custom synthesis and process development in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	(2S,4S,5R,6R)-5-Acetamido-6-(1-Acetyloxy-2,3-Dihydroxypropyl)-2,4-Dihydroxyoxane-2-Carboxylic Acid
CAS No.	18529-63-0
Molecular Formula	C13H21NO10
Molecular Weight	351.31 g/mol
Synonyms	5-Acetamido-6-(1-acetyloxy-2,3-dihydroxypropyl)-2,4-dihydroxyoxane-2-carboxylic acid; N-Acetylneuraminic acid 9-acetate; Neu5Ac9Ac; 9-O-Acetyl-N-acetylneuraminic acid; 9-Acetyl-N-acetylneuraminic acid; Sialic acid 9-acetate; 9-O-Acetylneuraminic acid; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2S,4S,5R,6R)-5-Acetamido-6-(1-Acetyloxy-2,3-Dihydroxypropyl)-2,4-Dihydroxyoxane-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.