Description

2-[(1R)-1-(2,4,5-Trimethoxyphenyl)-2-Propenyl]Phenol is a chiral phenolic compound featuring a unique propenyl side chain attached to a trimethoxyphenyl moiety. This specific stereochemistry and functional group arrangement make it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and fine chemical industries. The compound's structure is ideal for constructing complex molecules where stereochemical control and specific aromatic substitution patterns are critical.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or cardiovascular targets.
• Asymmetric Synthesis Building Block: Utilized in the development of novel catalysts and ligands for enantioselective reactions due to its defined stereocenter.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the discovery of new chemical entities for drug development programs.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials requiring high-purity intermediates.
• Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Product Name	2-[(1R)-1-(2,4,5-Trimethoxyphenyl)-2-Propenyl]Phenol
CAS No.	18525-14-9
Molecular Formula	C18H20O4
Molecular Weight	300.35 g/mol
Synonyms	(R)-2-[1-(2,4,5-Trimethoxyphenyl)allyl]phenol; Phenol, 2-[(1R)-1-(2,4,5-trimethoxyphenyl)-2-propen-1-yl]-; 2-[(1R)-1-(2,4,5-Trimethoxyphenyl)allyl]phenol; (R)-2-(1-(2,4,5-Trimethoxyphenyl)prop-2-en-1-yl)phenol; 18525-14-9; (R)-enantiomer of the trimethoxyphenyl propenyl phenol derivative.
EINECS	Contact for details

Quality Control

Our 2-[(1R)-1-(2,4,5-Trimethoxyphenyl)-2-Propenyl]Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, strength, and purity. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles. Our commitment to consistent quality and supply reliability supports critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct or strong artificial light.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.