Description

2-O,3-O,5-o-Trimethyl-L-Arabinofuranose is a key protected monosaccharide derivative, specifically a fully methylated furanose form of L-arabinose. This compound is highly valued as a crucial chiral building block and synthetic intermediate in advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of nucleoside analogs, carbohydrate-based drugs, and complex natural products.

Application

• Pharmaceutical Intermediate: Serves as a vital precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Chiral Building Block: Used in asymmetric synthesis to introduce the L-arabinose configuration into complex molecules, leveraging its protected hydroxyl groups for selective functionalization.
• Glycochemistry Research: Essential for constructing oligosaccharides, glycoconjugates, and glycomimetics in academic and industrial research settings.
• Agrochemical Synthesis: Employed in the development of advanced, bioactive compounds where specific sugar moieties are required for activity.
• Fine Chemical Production: Acts as a starting material for specialty chemicals, flavors, and fragrances that require high-purity, optically active intermediates.
• Process Chemistry: Used in scale-up and route development for APIs (Active Pharmaceutical Ingredients) requiring robust and reproducible glycosylation steps.

Basic Information

Product Name	2-O,3-O,5-o-Trimethyl-L-Arabinofuranose
CAS No.	18463-35-9
Molecular Formula	C8H16O5
Molecular Weight	192.21 g/mol
Synonyms	1,2,3,5-Tetra-O-methyl-L-arabinofuranose; 2,3,5-Tri-O-methyl-L-arabinofuranose; L-Arabinofuranose, 2,3,5-trimethyl-; Methyl 2,3,5-tri-O-methyl-L-arabinofuranoside; 1,2,3,5-Tetramethyl-L-arabinofuranose; Trimethyl-L-arabinofuranose; 2,3,5-Trimethyl arabinofuranose
EINECS	Contact for details

Quality Control

Our 2-O,3-O,5-o-Trimethyl-L-Arabinofuranose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR) to ensure consistent identity and high purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	Contact for details
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.