Description

trans-Alpha,4-Dimethylcyclohexane-1-Methanol is a high-purity, stereochemically defined cyclohexane derivative used as a critical chiral intermediate and building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it valuable for constructing complex molecular architectures with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty fragrance industries who require high-quality, consistent intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical purity.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and pesticides where specific isomer configuration impacts biological activity.
• Fragrance & Flavor Chemistry: Serves as a precursor for musky, woody, or amber odorants in high-value perfumery and flavor compounds.
• Ligand & Catalyst Development: Employed in the research and manufacture of chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or modifier in the development of specialized polymers and liquid crystals.
• Chemical Reference Standard: Provides a certified standard for analytical method development and quality control in chemical analysis.

Basic Information

Product Name	trans-Alpha,4-Dimethylcyclohexane-1-Methanol
CAS No.	18446-94-1
Molecular Formula	C9H18O
Molecular Weight	142.24 g/mol
Synonyms	trans-1-Hydroxymethyl-2,5-dimethylcyclohexane; (1R,2R)-2,5-Dimethylcyclohexanemethanol; (1S,2S)-2,5-Dimethylcyclohexanemethanol; 2,5-Dimethylcyclohexanemethanol (trans-); trans-2,5-Dimethylcyclohexylmethanol; Cyclohexanemethanol, 2,5-dimethyl-, trans-; NSC 163082
EINECS	Contact for details

Quality Control

Our trans-Alpha,4-Dimethylcyclohexane-1-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and isomer content are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Isomeric Content)	≥ 98.0% trans-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.