Description

tert-Butyl 4-Nitrophenylcarbamate is a high-purity chemical intermediate of significant importance in advanced organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and other specialized applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing carbamate or aniline functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Peptide Chemistry: Serves as a protected amine precursor in solid-phase peptide synthesis (SPPS) and other peptide coupling methodologies.
• Polymer Science: Intermediate for the development of specialty polymers and functional materials.
• Organic Synthesis Reagent: Employed in laboratory-scale and industrial organic reactions, including nucleophilic substitutions and catalytic transformations.
• Chemical Research: Valuable reference standard and starting material in academic and industrial R&D for novel compound libraries.

Basic Information

Product Name	tert-Butyl 4-Nitrophenylcarbamate
CAS No.	18437-63-3
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	tert-Butyl N-(4-Nitrophenyl)carbamate; 4-Nitrophenylcarbamic Acid tert-Butyl Ester; 1-(tert-Butoxycarbonylamino)-4-nitrobenzene; BOC-4-Nitroaniline; N-Boc-4-nitroaniline; N-(tert-Butoxycarbonyl)-4-nitroaniline; tert-Butyl (4-nitrophenyl)carbamate; Carbamic acid, N-(4-nitrophenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Nitrophenylcarbamate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.