Description

4-Chloro-7-Nitroquinoline is a versatile and high-value heterocyclic building block, recognized for its unique chemical structure that combines a halogenated quinoline core with a nitro functional group. This compound is essential for facilitating complex synthetic transformations in advanced organic chemistry and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those with quinoline-based pharmacophores for potential antimicrobial, anticancer, or anti-inflammatory activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its bioactive quinoline scaffold.
• Organic Synthesis Building Block: Serves as a versatile substrate for nucleophilic aromatic substitution (SNAr) reactions, metal-catalyzed cross-couplings, and reduction reactions to generate diverse aminoquinoline derivatives.
• Material Science: Investigated as a starting material for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), or photoactive compounds.
• Dye and Pigment Chemistry: Acts as an intermediate in the synthesis of specialized nitro-substituted quinoline dyes and colorants.

Basic Information

Product Name	4-Chloro-7-Nitroquinoline
CAS No.	18436-76-5
Molecular Formula	C9H5ClN2O2
Molecular Weight	208.60 g/mol
Synonyms	7-Nitro-4-chloroquinoline; 4-Chloro-7-nitroquinoline; Quinoline, 4-chloro-7-nitro-; 18436-76-5; 4-Chlor-7-nitrochinolin; 4-Cl-7-NO2-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Nitroquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.