Description

Semicarbazide Hydrochloride is a versatile organic salt widely used as a key reagent in chemical synthesis and analytical chemistry. Its primary value lies in its reactivity as a carbonyl-trapping agent, enabling the formation of semicarbazones for the identification, purification, and protection of aldehydes and ketones. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular construction and analysis are critical.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing hydrazine or carbonyl-reactive moieties.
• Analytical Chemistry Reagent: Used for the derivatization and identification of carbonyl compounds (aldehydes and ketones) via semicarbazone formation in chromatography and spectroscopy.
• Fine Chemical Synthesis: Serves as a precursor and reagent in the production of heterocyclic compounds, dyes, and other specialty chemicals.
• Biochemical Research: Employed in protein chemistry and enzymology studies as a modifying agent for specific functional groups.
• Polymer Chemistry: Can be utilized as a cross-linking agent or monomer in the development of specialty polymeric materials.
• Agrochemical Manufacturing: Acts as an intermediate in the synthesis of certain herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	Semicarbazide Hydrochloride
CAS No.	18396-65-1
Molecular Formula	CH6ClN3O
Molecular Weight	111.53 g/mol
Synonyms	Aminourea Hydrochloride; Carbamylhydrazine Hydrochloride; Hydrazinecarboxamide Hydrochloride; Urea, 1-Amino-, Monohydrochloride; Semicarbazide HCl; Semicarbazide Monohydrochloride; NSC 1891
EINECS	242-247-8

Quality Control

Our Semicarbazide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent decomposition. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Melting Point	175 - 185 °C (decomposes)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.