Description

n-Trimethylsilyl-n-n-Butyl-N',N'-Diethylurea is a specialized organosilicon reagent primarily used as a silylating agent in organic synthesis. This compound matters for its ability to protect reactive functional groups, such as hydroxyls and amines, facilitating complex multi-step reactions in sensitive chemical processes. It is needed by research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the production of active ingredients and novel compounds.

Application

• As a silylating agent for the protection of hydroxyl and amino groups in complex organic synthesis.
• Key intermediate in the pharmaceutical industry for the production of active pharmaceutical ingredients (APIs) and fine chemicals.
• Used in agrochemical research for the synthesis of novel pesticides and herbicides.
• Facilitates peptide synthesis by protecting sensitive functional groups during coupling reactions.
• Employed in the development of advanced materials, including silicon-based polymers and coatings.
• Useful in analytical chemistry for derivatizing compounds to improve their volatility for GC-MS analysis.

Basic Information

Product Name	n-Trimethylsilyl-n-n-Butyl-N',N'-Diethylurea
CAS No.	18388-99-3
Molecular Formula	C₁₂H₂₈N₂OSi
Molecular Weight	244.45 g/mol
Synonyms	1-Butyl-3-(trimethylsilyl)-1,3-diethylurea; N-Trimethylsilyl-N-butyl-N',N'-diethylurea; TBDU; Trimethylsilyl Diethyl Butyl Urea; N-Butyl-N'-trimethylsilyl-N,N'-diethylurea; Urea, N-butyl-N'-(trimethylsilyl)-N,N'-diethyl-; 1,3-Diethyl-1-butyl-3-(trimethylsilyl)urea
EINECS	Contact for details

Quality Control

Our n-Trimethylsilyl-n-n-Butyl-N',N'-Diethylurea is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and industrial applications. Each lot undergoes rigorous analytical testing, including chromatography and spectroscopy, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.