Description

2-Oxo-1-Oxa-Spiro[4.4]Nonane-4-Carboxylic Acid is a high-value, multifunctional spirocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique fused ring structure containing both lactone and carboxylic acid functionalities makes it an indispensable intermediate for creating complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides with novel modes of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: The spirocyclic framework is utilized to construct sophisticated chiral ligands for asymmetric catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex macrocyclic musk analogs and other specialty aroma chemicals.

Basic Information

Product Name	2-Oxo-1-Oxa-Spiro[4.4]Nonane-4-Carboxylic Acid
CAS No.	18363-10-5
Molecular Formula	C9H12O4
Molecular Weight	184.19 g/mol
Synonyms	4-Carboxy-2-oxo-1-oxaspiro[4.4]nonane; 1-Oxa-2-oxospiro[4.4]nonane-4-carboxylic acid; Spiro[4.4]nonane-4-carboxylic acid, 2-oxo-1-oxa-; 2-Oxo-1-oxaspiro[4.4]nonane-4-carboxylic acid; 4-Carboxy-2-oxo-1-oxaspiro[4.4]nonane
EINECS	Contact for details

Quality Control

Our production of 2-Oxo-1-Oxa-Spiro[4.4]Nonane-4-Carboxylic Acid adheres to a strict quality management system, ensuring batch-to-batch consistency and high purity for research and scale-up applications. All materials are characterized by modern analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.