Description

Acetoacetamide, 2-Hydroxy-2-Methyl- (8Ci) CAS NO 18354-48-8 is a versatile chemical intermediate characterized by its reactive acetoacetamide and hydroxyl functional groups. This compound is valued for its role in the synthesis of more complex molecules, particularly in fine chemical and pharmaceutical manufacturing. It is primarily needed by research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and performance chemicals requiring specific functional group transformations.
• Research & Development: Employed in organic synthesis laboratories for method development and the creation of novel chemical entities.
• Polymer Modification: Can be used to introduce reactive sites into polymer chains for cross-linking or to impart specific properties.
• Coordination Chemistry: Acts as a ligand or precursor for metal-organic frameworks (MOFs) and catalysts.

Basic Information

Product Name	Acetoacetamide, 2-Hydroxy-2-Methyl- (8Ci)
CAS No.	18354-48-8
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	2-Hydroxy-2-methylacetoacetamide; 3-Oxobutanamide, 2-hydroxy-2-methyl-; 2-Methyl-2-hydroxyacetoacetamide; 2-Hydroxy-2-methyl-3-oxobutanamide; Acetoacetamide, 2-hydroxy-2-methyl-; 2-Hydroxy-2-methyl-3-oxobutyramide; 3-Oxobutyramide, 2-hydroxy-2-methyl-
EINECS	Contact for details

Quality Control

Our Acetoacetamide, 2-Hydroxy-2-Methyl- is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.