Description

3,5-Dichloro-4-Nitropyridine n-Oxide is a versatile and highly functionalized heterocyclic building block. Its unique structure, featuring both chloro and nitro substituents on a pyridine N-oxide core, makes it a critical intermediate for synthesizing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables the efficient construction of novel active ingredients through targeted nucleophilic substitution and reduction reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for creating libraries of nitrogen-containing heterocycles with potential biological activity.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the chloro and nitro groups serve as handles for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers due to its electron-deficient aromatic system.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	3,5-Dichloro-4-Nitropyridine n-Oxide
CAS No.	18344-58-6
Molecular Formula	C5H2Cl2N2O3
Molecular Weight	208.99 g/mol
Synonyms	3,5-Dichloro-4-nitropyridine 1-oxide; 4-Nitro-3,5-dichloropyridine N-oxide; 3,5-Dichloro-4-nitropyridine N-oxide; Pyridine, 3,5-dichloro-4-nitro-, 1-oxide; 3,5-Dichloro-4-nitropyridine oxide; 4-Nitro-3,5-dichloropyridine 1-oxide
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-4-Nitropyridine n-Oxide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.