Description

Methylthiophosphorylchloride CAS NO 18281-76-0 is a key organophosphorus intermediate characterized by its high reactivity. This compound is essential for the synthesis of advanced agrochemicals and pharmaceuticals, where it serves as a critical building block for introducing thiophosphoryl functionalities. It is primarily utilized by research and development chemists and process engineers in the agrochemical, pharmaceutical, and specialty chemical manufacturing sectors.

Application

• Agrochemical Synthesis: A vital precursor in the manufacture of organophosphate and organothiophosphate insecticides, herbicides, and fungicides.
• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs requiring thiophosphoryl or phosphorothioate groups.
• Chemical Research: Serves as a versatile reagent in organic synthesis for constructing P-S-Cl bonds in novel compounds.
• Ligand and Catalyst Preparation: Employed in the development of specialized ligands for metal catalysis and coordination chemistry.
• Flame Retardant Production: An intermediate in the synthesis of certain phosphorus-based flame retardant additives.
• Polymer Modification: Used to introduce functional groups into polymer chains to alter material properties.

Basic Information

Product Name	Methylthiophosphorylchloride
CAS No.	18281-76-0
Molecular Formula	C1H3ClOPS
Molecular Weight	130.52 g/mol
Synonyms	Methylphosphonothioic Dichloride; Methylphosphonothioic Chloride; Thiophosphoryl Chloride, Methyl-; Methyl Thiophosphoryl Dichloride; Methylphosphonothioyl Dichloride; O-Methyl Phosphorothiochloridate; Methylphosphonothioic Acid Dichloride; NSC 241081
EINECS	242-166-7

Quality Control

Our Methylthiophosphorylchloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, oxidizing agents, and moisture. Due to its nature as a strong acid/organic solvent and highly volatile compound, storage temperature should be maintained between 2°C and 8°C for optimal stability. Keep container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.