Description

Spiro[5.5]Undecane-3-Carboxylic Acid is a specialized spirocyclic carboxylic acid building block valued for its unique three-dimensional structure and functional handle. This compound is essential for advanced research and development in medicinal chemistry, where it is used to modulate the physicochemical properties and conformational rigidity of novel drug candidates. It serves as a critical intermediate for pharmaceutical chemists, agrochemical researchers, and material scientists seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, where its spirocyclic core can enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials requiring rigid, non-planar molecular architectures.
• Chemical Biology: Employed as a molecular scaffold or linker in probe and tool compound development for studying biological systems.
• Catalyst & Ligand Development: The carboxylic acid group allows for derivatization into chiral ligands or organocatalysts for asymmetric synthesis.
• Fragrance & Flavor Chemistry: Potential intermediate for synthesizing complex musk-like odorants and flavor compounds due to its polycyclic framework.

Basic Information

Product Name	Spiro[5.5]Undecane-3-Carboxylic Acid
CAS No.	18244-47-8
Molecular Formula	C12H20O2
Molecular Weight	196.29 g/mol
Synonyms	3-Spiro[5.5]undecanecarboxylic acid; 3-Carboxyspiro[5.5]undecane; Spiro[5.5]undecane-3-carboxylic acid; 1,1-Pentamethylenepentane-5-carboxylic acid; 3-Carboxyspiro[5.5]undecane; 3-Spiro[5.5]undecanylcarboxylic acid
EINECS	Contact for details

Quality Control

Our Spiro[5.5]Undecane-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.