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[R,(+)]-2,8-Diacetyl-3,7,9-Trihydroxy-6,9B-Dimethyldibenzofuran-1(9Bh)-One CAS NO 18058-86-1


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CAS No.:18058-86-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[R,(+)]-2,8-Diacetyl-3,7,9-Trihydroxy-6,9B-Dimethyldibenzofuran-1(9Bh)-One is a high-purity, optically active dibenzofuran derivative characterized by its specific stereochemistry and functional groups. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex organic molecules, where its unique structure imparts specific biological or material properties. It is primarily needed by pharmaceutical research organizations, fine chemical manufacturers, and academic institutions engaged in developing novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key chiral precursor in the research and development of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
  • Asymmetric Synthesis: Utilized as a sophisticated starting material or ligand in catalytic asymmetric reactions to induce chirality in target molecules.
  • Natural Product Synthesis: Serves as a core structural motif in the total synthesis of complex natural products with dibenzofuran skeletons.
  • Material Science Research: Investigated for the development of organic electronic materials, liquid crystals, or specialty polymers due to its rigid, fused aromatic system.
  • Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies, leveraging its specific stereochemistry for target interaction.
  • Reference Standard: Sourced for use as an analytical standard in quality control and method development for related compounds.

Basic Information

Item Detail
Product Name [R,(+)]-2,8-Diacetyl-3,7,9-Trihydroxy-6,9B-Dimethyldibenzofuran-1(9Bh)-One
CAS No. 18058-86-1
Molecular Formula C20H18O7
Molecular Weight 370.35 g/mol
Synonyms (+)-Griffipavixanthone; (R)-Griffipavixanthone; (6aR,12bR)-2,8-Diacetyl-3,7,9-trihydroxy-1,6a,12b-trimethyl-6a,12b-dihydro-7H-chromeno[3,2-c]chromen-7-one; Griffipavixanthone; NSC 339588; 1(9bH)-Dibenzofuranone, 2,8-diacetyl-3,7,9-trihydroxy-6,9b-dimethyl-, (R)-; [R-(+)]-2,8-Diacetyl-3,7,9-trihydroxy-6,9b-dimethyldibenzofuran-1(9bH)-one
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Quality Control

Our [R,(+)]-2,8-Diacetyl-3,7,9-Trihydroxy-6,9B-Dimethyldibenzofuran-1(9Bh)-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item Specification
Appearance Yellow to light brown powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% ee
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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