Description

3-o-Benzyl-5,6-Di-o-Acetyl-1,2-o-Isopropylidene-A-D-Glucofuranose is a key protected carbohydrate intermediate, specifically a glucofuranose derivative with orthogonal protecting groups. This compound matters for its role as a versatile chiral building block in the synthesis of complex molecules, enabling precise control over stereochemistry and functional group manipulation. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for the production of nucleoside analogs, glycosidase inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of antiviral and anticancer nucleoside analogs.
• Glycoscience Research: Used in the study and development of glycosidase inhibitors and carbohydrate-based therapeutics.
• Agrochemical Synthesis: Serves as a building block for creating novel, biologically active molecules with specific stereochemical configurations.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring high stereoselectivity.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and scale-up process optimization.
• Glycoconjugate Synthesis: Used in the preparation of selectively protected sugar moieties for conjugation to proteins, lipids, or other carriers.

Basic Information

Product Name	3-o-Benzyl-5,6-Di-o-Acetyl-1,2-o-Isopropylidene-A-D-Glucofuranose
CAS No.	18006-25-2
Molecular Formula	C20H26O8
Molecular Weight	394.42 g/mol
Synonyms	1,2-O-Isopropylidene-3-O-benzyl-5,6-di-O-acetyl-α-D-glucofuranose; 3-O-Benzyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (common misnomer); 3-O-Benzyl-5,6-di-O-acetyl-1,2-O-isopropylidene-α-D-glucofuranose; 3-O-Benzyl-5,6-di-O-acetyl-1,2-O-(1-methylethylidene)-α-D-glucofuranose; α-D-Glucofuranose, 3-O-benzyl-5,6-di-O-acetyl-1,2-O-(1-methylethylidene)-; Benzyl-protected isopropylidene glucofuranose diacetate
EINECS	Contact for details

Quality Control

Our 3-o-Benzyl-5,6-Di-o-Acetyl-1,2-o-Isopropylidene-A-D-Glucofuranose is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.