Description

7-Methyl-8-Quinoxalinesulfonyl Chloride is a high-purity sulfonyl chloride derivative, a crucial reactive intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile electrophilic building block for introducing the 7-methyl-8-quinoxaline sulfonamide moiety, enabling the development of novel compounds with targeted functionalities. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating potential active ingredients, ligands, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, receptor antagonists, and other small molecule therapeutics.
• Agrochemical Research: Used in creating advanced fungicides, herbicides, and insecticides by serving as a precursor for sulfonamide-based active ingredients.
• Material Science: Employed in the synthesis of functional polymers, dyes, and photoactive materials where the quinolinesulfonyl group imparts specific electronic or binding properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation, labeling proteins, or creating activity-based probes (ABPs) due to its sulfonyl chloride reactivity with amines and alcohols.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic systems and for introducing sulfonamide linkages in target molecules.

Basic Information

Product Name	7-Methyl-8-Quinoxalinesulfonyl Chloride
CAS No.	17999-75-6
Molecular Formula	C10H7ClN2O2S
Molecular Weight	254.69 g/mol
Synonyms	8-Quinoxalinesulfonyl chloride, 7-methyl-; 7-Methylquinoxaline-8-sulfonyl chloride; 7-Methyl-8-quinoxaline sulfonyl chloride; 7-Methylquinoxaline-8-sulphonyl chloride; 17999-75-6; Quinoxaline-8-sulfonyl chloride, 7-methyl-; 7-Methyl-8-sulfonylchloride quinoxaline
EINECS	Contact for details

Quality Control

Our 7-Methyl-8-Quinoxalinesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.