Description

Diethyl Phthalide-3-Phosphonate is a specialized organophosphorus compound that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a phthalide and a phosphonate ester group, makes it a versatile building block for constructing complex molecular architectures. This high-purity reagent is essential for research and development laboratories and chemical production facilities engaged in pharmaceutical synthesis, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex heterocyclic frameworks.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific phosphonate functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphonate-based ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials where the incorporation of a rigid phthalide unit is beneficial.
• Academic and R&D Laboratories: A crucial reagent for methodological development in organic synthesis, including studies on cyclization reactions and C-P bond formation.
• Fine Chemical Production: Intermediate for manufacturing high-value specialty chemicals used in electronics, coatings, and other performance-driven industries.

Basic Information

Product Name	Diethyl Phthalide-3-Phosphonate
CAS No.	17858-15-0
Molecular Formula	C13H15O5P
Molecular Weight	282.23 g/mol
Synonyms	Diethyl (1,3-Dioxo-1,3-dihydro-2-benzofuran-3-yl)phosphonate; 3-(Diethoxyphosphoryl)phthalide; Phthalide-3-phosphonic Acid Diethyl Ester; Diethyl 3-Phosphonophthalate; 3-(Diethylphosphono)phthalide; 1,3-Dihydro-1,3-dioxo-2-benzofuran-3-ylphosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl Phthalide-3-Phosphonate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatographic purity analysis and spectroscopic identification, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.