Description

4-Cyclohexyl-1-Piperazinyl(3,4,5-Trimethoxyphenyl) Ketone is a high-purity, synthetic organic compound featuring a piperazine core linked to a trimethoxyphenyl ketone moiety via a cyclohexyl bridge. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and for structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities (NCEs) for high-throughput screening and lead optimization.
• Chemical Synthesis Reagent: Serves as a precursor for creating more complex piperazine and aryl ketone derivatives in organic synthesis.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and for studying protein-ligand interactions.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	4-Cyclohexyl-1-Piperazinyl(3,4,5-Trimethoxyphenyl) Ketone
CAS No.	17837-64-8
Molecular Formula	C20H30N2O4
Molecular Weight	362.47 g/mol
Synonyms	1-(4-Cyclohexylpiperazin-1-yl)-2-(3,4,5-trimethoxyphenyl)ethanone; 4-Cyclohexyl-1-piperazine(3,4,5-trimethoxyphenyl)methanone; (3,4,5-Trimethoxyphenyl)(4-cyclohexyl-1-piperazinyl)methanone; 4-Cyclohexylpiperazinyl 3,4,5-trimethoxyphenyl ketone; 17837-64-8; Cyclohexyl-piperazinyl-trimethoxyphenyl ketone
EINECS	Contact for details

Quality Control

Our 4-Cyclohexyl-1-Piperazinyl(3,4,5-Trimethoxyphenyl) Ketone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.