Description

1-Bromo-2,4-dimethoxybenzene is a versatile brominated aromatic ether, serving as a critical building block in advanced organic synthesis. Its value lies in its dual methoxy substituents, which direct subsequent electrophilic substitution and make it a key precursor for complex molecules. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds with complex aromatic ether backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where the bromine atom facilitates further functionalization.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers due to its stable aromatic structure and modifiable functional groups.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and organic pigments, leveraging its bromine for color-forming reactions.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	1-Bromo-2,4-dimethoxybenzene
CAS No.	17715-69-4
Molecular Formula	C8H9BrO2
Molecular Weight	217.06 g/mol
Synonyms	2,4-Dimethoxybromobenzene; 2-Bromo-1,3-dimethoxybenzene; 3-Bromo-1,5-dimethoxybenzene; 2,4-Dimethoxy-1-bromobenzene; Benzene, 1-bromo-2,4-dimethoxy-; 1,3-Dimethoxy-2-bromobenzene; 4-Bromo-1,3-dimethoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,4-dimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.