Description

Bis(2,2,2-Trichloroethyl) Phosphorochloridate is a specialized organophosphorus compound that serves as a critical phosphorylating and chlorinating agent in advanced chemical synthesis. Its high reactivity makes it a valuable intermediate for constructing complex molecules, particularly in the development of pharmaceuticals, agrochemicals, and flame retardants. This product is essential for R&D chemists and process engineers in fine chemical and life science industries seeking to introduce phosphonate or phosphate ester functionalities under controlled conditions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleotide analogs, prodrugs, and other bioactive phosphate esters.
• Agrochemical Synthesis: Used in the production of organophosphate insecticides and herbicides, where it acts as a phosphorylating agent.
• Flame Retardant Precursor: Intermediate in the manufacture of halogenated phosphate ester flame retardants for polymers and textiles.
• Chemical Research & Development: Valuable reagent for introducing the bis(2,2,2-trichloroethyl) phosphate (TCEP) protecting group in complex organic synthesis.
• Polymer Modification: Agent for the phosphorylation of polymers to alter material properties such as flame resistance or adhesion.
• Ligand and Catalyst Preparation: Used in the synthesis of specialized phosphonate ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	Bis(2,2,2-Trichloroethyl) Phosphorochloridate
CAS No.	17672-53-6
Molecular Formula	C4H4Cl7O3P
Molecular Weight	404.16 g/mol
Synonyms	Phosphorochloridic Acid, Bis(2,2,2-trichloroethyl) Ester; 2,2,2-Trichloroethyl Phosphorodichloridate; Bis(trichloroethyl) Chlorophosphate; TCECP; Chlorophosphoric Acid Bis(2,2,2-Trichloroethyl) Ester; Dichloridophosphoric Acid Bis(2,2,2-Trichloroethyl) Ester; NSC 84260
EINECS	241-654-7

Quality Control

Our Bis(2,2,2-Trichloroethyl) Phosphorochloridate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by titration and impurity profile analysis by GC/HPLC, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/Titration)	≥ 97.0%
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.70 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.