Description

Valine Benzyl Ester is a protected amino acid derivative, specifically the benzyl ester of L-valine, widely used as a crucial chiral building block in organic synthesis. Its primary value lies in enabling the controlled synthesis of peptides and complex molecules while protecting the carboxylic acid functionality from unwanted side reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing active pharmaceutical ingredients (APIs), peptide-based therapeutics, and advanced materials.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation & Probe Development: Used to incorporate the valine moiety into fluorescent probes, biomarkers, and other bioconjugates for research and diagnostics.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct stereogenic centers.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, custom catalysts, and advanced polymeric materials.
• Academic & Industrial R&D: A fundamental reagent for method development and exploratory chemistry in research laboratories.

Basic Information

Product Name	Valine Benzyl Ester
CAS No.	17645-51-1
Molecular Formula	C₁₂H₁₇NO₂
Molecular Weight	207.27 g/mol
Synonyms	L-Valine benzyl ester; Benzyl L-valinate; (S)-2-Amino-3-methylbutanoic acid benzyl ester; Val-OBzl; H-Val-OBzl; Valine, benzyl ester; Benzyl valinate; NSC 3349
EINECS	Contact for details

Quality Control

Our Valine Benzyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.