Description

(S)-2-Phenyl-1-Propylamine is a chiral amine building block of significant importance in asymmetric synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with high stereochemical purity. This compound is primarily needed by pharmaceutical research and development teams, agrochemical manufacturers, and fine chemical producers for applications in chiral catalyst development and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand: Serves as a precursor for the development of chiral ligands used in metal-catalyzed asymmetric reactions, such as hydrogenation and C-C bond formation.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where the specific stereochemistry can impact biological activity and environmental safety.
• Fine Chemical Building Block: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring precise stereocontrol.
• Chiral Resolution Agent: Can be utilized to resolve racemic mixtures of carboxylic acids or other compounds through diastereomeric salt formation.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways in process chemistry.

Basic Information

Product Name	(S)-2-Phenyl-1-Propylamine
CAS No.	17596-79-1
Molecular Formula	C9H13N
Molecular Weight	135.21 g/mol
Synonyms	(S)-(-)-α-Methylbenzylamine; (S)-1-Phenylethylamine; (S)-α-Methylbenzylamine; (S)-1-Amino-1-phenylethane; (S)-Phenylethylamine; (S)-PEA; (S)-Amphetamine (base); (S)-2-Amino-1-phenylethane; L-(-)-α-Methylbenzylamine
EINECS	Contact for details

Quality Control

Our (S)-2-Phenyl-1-Propylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]	-39° to -42° (c=1 in methanol)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.