Description

4-Chloro-2,3-dihydrofuran is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its reactive chloro and olefin functionalities, which enable its use as a key intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing functionalized tetrahydrofuran or dihydrofuran motifs.
• Agrochemical Synthesis: Used in the development and production of novel herbicides, fungicides, and insecticides, leveraging its reactivity to introduce chlorinated heterocyclic structures.
• Organic Synthesis Building Block: Acts as a versatile electrophile and dienophile in cycloaddition reactions, nucleophilic substitutions, and ring-opening polymerizations to create complex organic molecules.
• Material Science Research: Employed in the development of specialty polymers, resins, and liquid crystals where the incorporation of a chlorinated furan unit modifies physical and chemical properties.
• Cross-Coupling Reactions: Functions as a substrate in metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation in fine chemical synthesis.
• Chemical Research & Development: A valuable reagent for methodological studies and exploring new synthetic pathways in academic and industrial laboratories.

Basic Information

Product Name	4-Chloro-2,3-dihydrofuran
CAS No.	17557-40-3
Molecular Formula	C4H5ClO
Molecular Weight	104.54 g/mol
Synonyms	4-Chloro-2,5-dihydrofuran; 3-Chloro-2,5-dihydrofuran; 4-Chlorodihydrofuran; 2,3-Dihydro-4-chlorofuran; 4-Chloro-2,3-dihydrofuran; 4-Chloro-2,5-dihydrofuran; 4-Chloro-4,5-dihydrofuran; 4-Chloro-δ²-dihydrofuran
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,3-dihydrofuran is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for extended stability. Keep container tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.