Description

Z-p-Fluoro-Phe-Oh is a fluorinated aromatic amino acid derivative, specifically the Z-protected (benzyloxycarbonyl) form of para-fluorophenylalanine. This compound serves as a critical building block in advanced organic synthesis, where the fluorine atom and orthogonal protecting group enable precise structural modifications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, enzyme inhibitors, and specialized chemical probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated peptide drugs and bioactive molecules.
• Proteomics Research: Used to incorporate stable, non-natural amino acids into peptides for structure-activity relationship (SAR) studies.
• Chemical Biology: Serves as a building block for creating fluorinated analogs of natural products to study metabolic pathways.
• Agrochemical Development: Intermediate in the research and synthesis of novel fluorinated pesticides or herbicides.
• Material Science: Potential monomer for synthesizing specialized polymers with unique electronic or surface properties.
• Diagnostic Agent Synthesis: Used in the development of fluorinated tracers or contrast agents for imaging technologies.

Basic Information

Product Name	Z-p-Fluoro-Phe-Oh
CAS No.	17543-58-7
Molecular Formula	C17H16FNO4
Molecular Weight	317.31 g/mol
Synonyms	N-Carbobenzoxy-4-fluorophenylalanine; Z-4-Fluoro-DL-phenylalanine; Cbz-4-F-Phe-OH; Benzyl N-(4-fluorophenylalanyl)carbamate; N-[(Benzyloxy)carbonyl]-4-fluorophenylalanine; (RS)-2-[(Benzyloxycarbonyl)amino]-3-(4-fluorophenyl)propanoic acid; 4-Fluoro-DL-phenylalanine, N-carbobenzoxy-; Z-F4-Phe-OH
EINECS	Contact for details

Quality Control

Our Z-p-Fluoro-Phe-Oh is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis where applicable, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.