Description

Diethyl 1-Hydroxybutylphosphonate is a versatile organophosphorus compound that serves as a key intermediate in advanced organic synthesis. Its unique structure, featuring both a phosphonate ester and a hydroxyl group, makes it a valuable building block for creating complex molecules with tailored properties. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting bone diseases or requiring phosphonate-based bioisosteres.
• Agrochemical Synthesis: Serves as a precursor for herbicides, plant growth regulators, and other crop protection agents with phosphonate moieties.
• Ligand and Catalyst Preparation: Employed in the development of chiral ligands for asymmetric catalysis and metal-complexing agents.
• Flame Retardant Synthon: Acts as a reactive intermediate in the production of phosphorus-containing flame retardants for polymers and textiles.
• Material Science Research: Utilized in the creation of functionalized surfaces, metal-organic frameworks (MOFs), and other advanced materials.
• Chemical Biology Probes: A building block for synthesizing activity-based probes and enzyme inhibitors that mimic natural phosphates.

Basic Information

Product Name	Diethyl 1-Hydroxybutylphosphonate
CAS No.	17477-67-7
Molecular Formula	C8H19O4P
Molecular Weight	210.21 g/mol
Synonyms	1-Hydroxybutylphosphonic Acid Diethyl Ester; Diethyl (1-Hydroxybutyl)phosphonate; Butan-1-ol, 1-(diethoxyphosphinyl)-; (1-Hydroxybutyl)phosphonic Acid Diethyl Ester; Diethyl α-Hydroxybutylphosphonate; Phosphonic Acid, (1-Hydroxybutyl)-, Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl 1-Hydroxybutylphosphonate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.